Size-independent symmetric division in extraordinarily long cells

Autor(en)
Nika Pende, Nikolaus Leisch, Harald R. Gruber-Vodicka, Niels R. Heindl, Joerg Ott, Tanneke den Blaauwen, Silvia Bulgheresi
Abstrakt

Two long-standing paradigms in biology are that cells belonging to the same population exhibit little deviation from their average size and that symmetric cell division is size limited. Here, ultrastructural, morphometric and immunocytochemical analyses reveal that two Gammaproteobacteria attached to the cuticle of the marine nematodes Eubostrichus fertilis and E. dianeae reproduce by constricting a single FtsZ ring at midcell despite being 45 €‰ 1/4m and 120 €‰ 1/4m long, respectively. In the crescent-shaped bacteria coating E. fertilis, symmetric FtsZ-based fission occurs in cells with lengths spanning one order of magnitude. In the E. dianeae symbiont, formation of a single functional FtsZ ring makes this the longest unicellular organism in which symmetric division has ever been observed. In conclusion, the reproduction modes of two extraordinarily long bacterial cells indicate that size is not the primary trigger of division and that yet unknown mechanisms time the localization of both DNA and the septum.

Organisation(en)
Department für Funktionelle und Evolutionäre Ökologie
Externe Organisation(en)
Max-Planck-Institut für marine Mikrobiologie, Medizinische Universität Wien, University of Amsterdam (UvA)
Journal
Nature Communications
Band
5
Anzahl der Seiten
10
ISSN
2041-1723
DOI
https://doi.org/10.1038/ncomms5803
Publikationsdatum
09-2014
Peer-reviewed
Ja
ÖFOS 2012
106052 Zellbiologie, 106022 Mikrobiologie
Schlagwörter
ASJC Scopus Sachgebiete
Allgemeine Physik und Astronomie, Allgemeine Chemie, Allgemeine Biochemie, Genetik und Molekularbiologie
Sustainable Development Goals
SDG 14 – Leben unter Wasser
Link zum Portal
https://ucrisportal.univie.ac.at/de/publications/dfa5de43-8acc-4e74-9577-ec772c0e8532