Stepwise pathway for early evolutionary assembly of dissimilatory sulfite and sulfate reduction

Autor(en)

Sinje Neukirchen, Inês A C Pereira, Maria Filipa Baltazar de Lima de Sousa

Abstrakt

Microbial dissimilatory sulfur metabolism utilizing dissimilatory sulfite reductases (Dsr) influenced the biochemical sulfur cycle during Earth’s history and the Dsr pathway is thought to be an ancient metabolic process. Here we performed comparative genomics, phylogenetic, and synteny analyses of several Dsr proteins involved in or associated with the Dsr pathway across over 195,000 prokaryotic metagenomes. The results point to an archaeal origin of the minimal DsrABCMK(N) protein set, having as primordial function sulfite reduction. The acquisition of additional Dsr proteins (DsrJOPT) increased the Dsr pathway complexity. Archaeoglobus would originally possess the archaeal-type Dsr pathway and the archaeal DsrAB proteins were replaced with the bacterial reductive-type version, possibly at the same time as the acquisition of the QmoABC and DsrD proteins. Further inventions of two Qmo complex types, which are more spread than previously thought, allowed microorganisms to use sulfate as electron acceptor. The ability to use the Dsr pathway for sulfur oxidation evolved at least twice, with Chlorobi and Proteobacteria being extant descendants of these two independent adaptations.

Organisation(en)

Department für Funktionelle und Evolutionäre Ökologie

Externe Organisation(en)

Universidade Nova de Lisboa

Journal

The ISME Journal

Band

17

Seiten

1680-1692

Anzahl der Seiten

13

ISSN

1751-7362

DOI

https://doi.org/10.1038/s41396-023-01477-y

Publikationsdatum

2023

Peer-reviewed

Ja

ÖFOS 2012

106014 Genomik

ASJC Scopus Sachgebiete

Ecology, Evolution, Behavior and Systematics, Microbiology

Link zum Portal

https://ucris.univie.ac.at/portal/de/publications/stepwise-pathway-for-early-evolutionary-assembly-of-dissimilatory-sulfite-and-sulfate-reduction(89f01d9c-7f91-4164-9294-eeaa4dfc10ae).html