Stepwise pathway for early evolutionary assembly of dissimilatory sulfite and sulfate reduction

Autor(en)
Sinje Neukirchen, Inês A C Pereira, Maria Filipa Baltazar de Lima de Sousa
Abstrakt

Microbial dissimilatory sulfur metabolism utilizing dissimilatory sulfite reductases (Dsr) influenced the biochemical sulfur cycle during Earth’s history and the Dsr pathway is thought to be an ancient metabolic process. Here we performed comparative genomics, phylogenetic, and synteny analyses of several Dsr proteins involved in or associated with the Dsr pathway across over 195,000 prokaryotic metagenomes. The results point to an archaeal origin of the minimal DsrABCMK(N) protein set, having as primordial function sulfite reduction. The acquisition of additional Dsr proteins (DsrJOPT) increased the Dsr pathway complexity. Archaeoglobus would originally possess the archaeal-type Dsr pathway and the archaeal DsrAB proteins were replaced with the bacterial reductive-type version, possibly at the same time as the acquisition of the QmoABC and DsrD proteins. Further inventions of two Qmo complex types, which are more spread than previously thought, allowed microorganisms to use sulfate as electron acceptor. The ability to use the Dsr pathway for sulfur oxidation evolved at least twice, with Chlorobi and Proteobacteria being extant descendants of these two independent adaptations.

Organisation(en)
Department für Funktionelle und Evolutionäre Ökologie
Externe Organisation(en)
Universidade Nova de Lisboa
Journal
The ISME Journal
Band
17
Seiten
1680-1692
Anzahl der Seiten
13
ISSN
1751-7362
DOI
https://doi.org/10.1038/s41396-023-01477-y
Publikationsdatum
2023
Peer-reviewed
Ja
ÖFOS 2012
106014 Genomik
ASJC Scopus Sachgebiete
Ecology, Evolution, Behavior and Systematics, Microbiology
Link zum Portal
https://ucrisportal.univie.ac.at/de/publications/stepwise-pathway-for-early-evolutionary-assembly-of-dissimilatory-sulfite-and-sulfate-reduction(89f01d9c-7f91-4164-9294-eeaa4dfc10ae).html