Quantitative Analysis of Core Lipid Production in Methanothermobacter marburgensis at Different Scales

Autor(en)
Lydia M F Baumann, Ruth-Sophie Taubner, Kinga Oláh, Ann-Cathrin Rohrweber, Bernhard Schuster, Daniel Birgel, Simon K-M R Rittmann
Abstrakt

Archaeal lipids have a high biotechnological potential, caused by their high resistance to oxidative stress, extreme pH values and temperatures, as well as their ability to withstand phospholipases. Further, methanogens, a specific group of archaea, are already well-established in the field of biotechnology because of their ability to use carbon dioxide and molecular hydrogen or organic substrates. In this study, we show the potential of the model organism Methanothermobacter marburgensis to act both as a carbon dioxide based biological methane producer and as a potential supplier of archaeal lipids. Different cultivation settings were tested to gain an insight into the optimal conditions to produce specific core lipids. The study shows that up-scaling at a constant particle number (n/n = const.) seems to be a promising approach. Further optimizations regarding the length and number of the incubation periods and the ratio of the interaction area to the total liquid volume are necessary for scaling these settings for industrial purposes.

Organisation(en)
Institut für Geologie, Forschungsgruppe Theory and Applications of Algorithms, Department für Funktionelle und Evolutionäre Ökologie
Externe Organisation(en)
Universität Hamburg, Johannes Kepler Universität Linz, Universität für Bodenkultur Wien, Arkeon GmbH
Journal
Bioengineering : open access journal
Band
9
Anzahl der Seiten
16
ISSN
2306-5354
DOI
https://doi.org/10.3390/bioengineering9040169
Publikationsdatum
04-2022
Peer-reviewed
Ja
ÖFOS 2012
209003 Biotreibstoffe
Schlagwörter
ASJC Scopus Sachgebiete
Bioengineering
Link zum Portal
https://ucrisportal.univie.ac.at/de/publications/quantitative-analysis-of-core-lipid-production-in-methanothermobacter-marburgensis-at-different-scales(8343ea38-83c7-4616-ad6d-2db4eebcf77b).html