Quantitative Analysis of Core Lipid Production in Methanothermobacter marburgensis at Different Scales

Autor(en)

Lydia M F Baumann, Ruth-Sophie Taubner, Kinga Oláh, Ann-Cathrin Rohrweber, Bernhard Schuster, Daniel Birgel, Simon K-M R Rittmann

Abstrakt

Archaeal lipids have a high biotechnological potential, caused by their high resistance to oxidative stress, extreme pH values and temperatures, as well as their ability to withstand phospholipases. Further, methanogens, a specific group of archaea, are already well-established in the field of biotechnology because of their ability to use carbon dioxide and molecular hydrogen or organic substrates. In this study, we show the potential of the model organism Methanothermobacter marburgensis to act both as a carbon dioxide based biological methane producer and as a potential supplier of archaeal lipids. Different cultivation settings were tested to gain an insight into the optimal conditions to produce specific core lipids. The study shows that up-scaling at a constant particle number (n/n = const.) seems to be a promising approach. Further optimizations regarding the length and number of the incubation periods and the ratio of the interaction area to the total liquid volume are necessary for scaling these settings for industrial purposes.

Organisation(en)

Institut für Geologie, Forschungsgruppe Theory and Applications of Algorithms, Department für Funktionelle und Evolutionäre Ökologie

Externe Organisation(en)

Universität Hamburg, Johannes Kepler Universität Linz, Universität für Bodenkultur Wien, Arkeon GmbH

Journal

Bioengineering : open access journal

Band

9

Anzahl der Seiten

16

ISSN

2306-5354

DOI

https://doi.org/10.3390/bioengineering9040169

Publikationsdatum

04-2022

Peer-reviewed

Ja

ÖFOS 2012

209003 Biotreibstoffe

Schlagwörter

ASJC Scopus Sachgebiete

Bioengineering

Link zum Portal

https://ucris.univie.ac.at/portal/de/publications/quantitative-analysis-of-core-lipid-production-in-methanothermobacter-marburgensis-at-different-scales(8343ea38-83c7-4616-ad6d-2db4eebcf77b).html