Unifying the global phylogeny and environmental distribution of ammonia-oxidising archaea based on amoA genes

Autor(en)
Ricardo J. Eloy Alves, Bui Quang Minh, Tim Urich, Arndt von Haeseler, Christa Schleper
Abstrakt

Ammonia-oxidising archaea (AOA) are ubiquitous and abundant in nature and play a major role in nitrogen cycling. AOA have been studied intensively based on the amoA gene (encoding ammonia monooxygenase subunit A), making it the most sequenced functional marker gene. Here, based on extensive phylogenetic and meta-data analyses of 33,378 curated archaeal amoA sequences, we define a highly resolved taxonomy and uncover global environmental patterns that challenge many earlier generalisations. Particularly, we show: (i) the global frequency of AOA is extremely uneven, with few clades dominating AOA diversity in most ecosystems; (ii) characterised AOA do not represent most predominant clades in nature, including soils and oceans; (iii) the functional role of the most prevalent environmental AOA clade remains unclear; and (iv) AOA harbour molecular signatures that possibly reflect phenotypic traits. Our work synthesises information from a decade of research and provides the first integrative framework to study AOA in a global context.

Organisation(en)
Department für Ökogenomik und Systembiologie, Department für Strukturbiologie und Computational Biology, Forschungsgruppe Bioinformatics and Computational Biology
Externe Organisation(en)
Ernst Moritz Arndt Universität Greifswald
Journal
Nature Communications
Band
9
Anzahl der Seiten
17
ISSN
2041-1723
DOI
https://doi.org/10.1038/s41467-018-03861-1
Publikationsdatum
04-2018
Peer-reviewed
Ja
ÖFOS 2012
Systembiologie
Schlagwörter
Link zum Portal
https://ucris.univie.ac.at/portal/de/publications/unifying-the-global-phylogeny-and-environmental-distribution-of-ammoniaoxidising-archaea-based-on-amoa-genes(75ac6b92-39b4-4d28-8114-8f1a0b0a25a3).html