New publication by Hodgskiss, Melcher, Kerou et al in ISME

31.01.2023

"Unexpected complexity of the ammonia monooxygenase in archaea"

Congratulations to Logan H. Hodgskiss, Michael Melcher, Melina Kerou, Weiqiang Chen, Rafael I. Ponce-Toledo, Savvas N. Savvides, Stefanie Wienkoop, Markus Hartl & Christa Schleper on their new publication in ISME:

 

"Unexpected complexity of the ammonia monooxygenase in archaea"

The ammonia monooxygenase (AMO) is a critical piece of the nitrification process in both archaea and bacteria. In this paper, the authors found three new subunits unique to archaea correlated with known archaeal AMO subunits using independent proteomic, genomic, and transcriptomic approaches.  These new subunits appear to replace missing pieces of the archaeal complex and further highlight the physiological differences between ammonia oxidizing archaea and ammonia oxidizing bacteria.

 

 

Read the full article here: Unexpected complexity of the ammonia monooxygenase in archaea | The ISME Journal (nature.com)

Or download below.

 

Original paper:

ISME J (2023). doi.org/10.1038/s41396-023-01367-3

Unexpected complexity of the ammonia monooxygenase in archaea

Logan H. Hodgskiss, Michael Melcher, Melina Kerou, Weiqiang Chen, Rafael I. Ponce-Toledo, Savvas N. Savvides, Stefanie Wienkoop, Markus Hartl & Christa Schleper 

© Hodgskiss, Melcher, Kerou et al. Detail taken from Fig. 4: Structural support of proposed AMO subunits based on BN-PAGE cross-linking and AlphaFold modeling.

Logan Hodgskiss

Michael Melcher

Melina Kerou

Rafael Ponce Toledo

Christa Schleper