Isabelle Zink, Kevin Pfeiffer, Erika Wimmer,Uwe Sleytr, Bernhard Schuster and Christa Schleper have published their latest work in Nature Communications, entitled: "CRISPR-mediated gene silencing reveals involvement of the archaeal S-layer in cell division and virus infection" .
Isabelle, Kevin and the team set out to decipher the vital and often enigmatic roles of the proteinaceous outer layer of archaeal cells, the so-called S-layer, by investigating cells in which the respective genes were silenced by our previously published CRISPR-mediated gene silencing tool. Their exciting results offer crucial insights in the role of the S-layer in cell division.
Media coverage:
"Die nackte Wahrheit: Wenn ein Mikroorganismus seine Hüllen fallen lässt"
Wiener Zeitung (german only):
"Nackte Ur-Einzeller tun sich bei der Zellteilung schwer"
Die Presse (german only):
Publication in Nature Communications:
"CRISPR-mediated gene silencing reveals involvement of the archaeal S-layer in cell division and virus infection". Nature Communications 10, Article number: 4797 (2019)
DOI 10.1038/s41467-019-12745-x
Read Isabelle and Kevin's blog post discussing the highlights of the study here.
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