Size-independent symmetric division in extraordinarily long cells

Autor(en)

Nika Pende, Nikolaus Leisch, Harald R. Gruber-Vodicka, Niels R. Heindl, Joerg Ott, Tanneke den Blaauwen, Silvia Bulgheresi

Abstrakt

Two long-standing paradigms in biology are that cells belonging to the same population exhibit little deviation from their average size and that symmetric cell division is size limited. Here, ultrastructural, morphometric and immunocytochemical analyses reveal that two Gammaproteobacteria attached to the cuticle of the marine nematodes Eubostrichus fertilis and E. dianeae reproduce by constricting a single FtsZ ring at midcell despite being 45 €‰ 1/4m and 120 €‰ 1/4m long, respectively. In the crescent-shaped bacteria coating E. fertilis, symmetric FtsZ-based fission occurs in cells with lengths spanning one order of magnitude. In the E. dianeae symbiont, formation of a single functional FtsZ ring makes this the longest unicellular organism in which symmetric division has ever been observed. In conclusion, the reproduction modes of two extraordinarily long bacterial cells indicate that size is not the primary trigger of division and that yet unknown mechanisms time the localization of both DNA and the septum.

Organisation(en)

Department für Funktionelle und Evolutionäre Ökologie

Externe Organisation(en)

Max-Planck-Institut für marine Mikrobiologie, Medizinische Universität Wien, University of Amsterdam (UvA)

Journal

Nature Communications

Band

5

Anzahl der Seiten

10

ISSN

2041-1723

DOI

https://doi.org/10.1038/ncomms5803

Publikationsdatum

09-2014

Peer-reviewed

Ja

ÖFOS 2012

106052 Zellbiologie, 106022 Mikrobiologie

Schlagwörter

ASJC Scopus Sachgebiete

Physics and Astronomy(all), Chemistry(all), Biochemistry, Genetics and Molecular Biology(all)

Sustainable Development Goals

SDG 14 – Leben unter Wasser

Link zum Portal

https://ucris.univie.ac.at/portal/de/publications/sizeindependent-symmetric-division-in-extraordinarily-long-cells(dfa5de43-8acc-4e74-9577-ec772c0e8532).html